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Long COVID Can Make Exercise Debilitating Study Suggests. 'The Guardian' reports that many people suffering from long COVID can be left feeling tired and unwell for lengthy periods of time after exercising . Now, researchers believe they know the reason why. According to experts, evidence suggests that biological changes are the cause of the problem, including severe muscle damage, mitochondrial issues and micro blood clots. "It’s really confirming that there is something inside the body going wrong with the disease.", Dr. Rob Wüst, author of the study at Vrije Universiteit (Free University) Amsterdam, via 'The Guardian'. 'The Guardian' reports that long COVID is estimated to impact tens of thousands of people in Britain alone, with many experiencing worsening symptoms after exercise. Analysis of biopsies suggests that people with long COVID had more white fibers in their muscles than healthy participants in the study. Those fibers contain less power-producing mitochondria within their cells and fewer capillaries. The results also suggest that people with long COVID have more clumps of the protein amyloid in their skeletal muscles. Participants with long COVID experienced far more tissue damage after exercising and more signs that the body is attempting repairs. Dr. Rob Wüst, an author of the study at Vrije Universiteit (Free University) Amsterdam, told 'The Guardian' that the findings indicate that those with long COVID should avoid intense exercise. THIS VIDEO MUST NOT BE EDITED FOR LENGTH TO COMBINE WITH OTHER CONTENT